What is Gestanin?
Gestanin is a hormonal preparation designed for patients with progesterone deficiency. Its active ingredient is allylestrenol, a synthetic progestogen structurally related to progesterone. The medication is produced by various manufacturers and is sold under different trade names.
When is Gestanin indicated?
Gestanin is indicated during pregnancy to prevent miscarriage and premature labor due to progesterone deficiency in pregnant women. As far as the drug passes into the breast milk, it must be discontinued right after the delivery in order to avoid damage to the newly born child.
How to take Gestanin?
Gestanin should be taken as prescribed by the doctor. The dosage depends on severity of the disease, patient’s age and concomitant conditions. As a rule the drug is administered in a dose of one 5 mg tablet every 8 hours. In some cases it may be up-titrated to 5mg tablet every 6 hours, but the daily dosage shouldn’t exceed 4 tablets a day. The length of treatment must be established by the doctor as well. As long as it is a hormonal preparation, gradual withdrawal is recommended to avoid side effects.
What are Gestanin side effects?
Gestanin minor side effects, which can be eliminated through a dose reduction, are: nausea, vomiting, indigestion and diarrhea. Serious side effects, which require immediate medical attention are: such allergic reactions as swelling of lips, tongue or mouth, itching, hives and difficulty breathing. Some patients may require careful monitoring while on the drug.
When is Gestanin contraindicated?
Gestanin is contraindicated to children under 16. Patients with heart diseases, sinus syndrome, epilepsy, seizures, renal dysfunction and migraine associated with hormonal changes, as well as patients with such respiratory diseases as bronchitis, asthma, emphysema or chronic obstructive pulmonary disease are not recommended to take this drug and require administration of alternative pharmacological class drugs.